Top 10 Supplements for Energy and Focus in 2025

In a world moving faster than ever, staying energised and focused is no longer optional — it’s essential. Whether you're a creator pulling long editing sessions, an entrepreneur juggling projects, or simply someone striving for better daily performance, the right supplements can make all the difference.

We've rounded up the top 10 supplements for energy and focus in 2025, backed by science and used daily by high performers worldwide.

1. NMN (Nicotinamide Mononucleotide)

NMN is rapidly gaining attention for its role in boosting NAD+ levels, a molecule essential for cellular energy production. With age, our NAD+ levels decline, leading to fatigue and brain fog. NMN helps support energy metabolism, sharpens focus, and even promotes healthy ageing.

Tip: Take NMN in the morning to support sustained energy throughout the day.

2. Lion’s Mane Mushroom

Lion’s Mane is nature’s nootropic. Known for stimulating the growth of brain cells and enhancing cognitive function, it’s a favourite among creators and entrepreneurs. Studies suggest it supports mental clarity, focus, and even mood.

Bonus: It also supports long-term brain health, making it a smart daily choice.

3. Magnesium Glycinate

While magnesium is famous for relaxation and sleep, Magnesium Glycinate specifically helps ease stress and support cognitive function. Stress drains mental energy fast — keeping your magnesium levels optimal supports both mind and body performance.

Best taken in the evening to aid recovery and restful sleep.

4. Creatine Monohydrate

Not just for athletes! Creatine enhances mental performance, especially during demanding tasks. Studies show it helps with brain energy metabolism and short-term memory. Creatine supports the production of ATP — your brain’s primary energy source.

Consider micro-dosing daily for cognitive benefits and mental stamina.

5. Vitamin D3 + K2

Vitamin D3 plays a critical role in energy regulation and immune support. Pairing it with Vitamin K2 improves absorption and supports cardiovascular health. Many people, especially in cloudy climates, are deficient without realising it.

Pro tip: Pair with healthy fats for better absorption.

6. L-Theanine + Caffeine Stack

This natural combo delivers clean energy without the jitters. Caffeine boosts alertness, while L-Theanine smooths out the stimulation, improving focus and calm at the same time.

Ideal for early work sessions or creative deep work.

7. Rhodiola Rosea

An adaptogen that helps your body handle stress and fatigue. Rhodiola is known for enhancing endurance and mental performance, especially during periods of high workload.

Take in the morning or before a demanding task.

8. Coenzyme Q10 (CoQ10)

CoQ10 plays a vital role in energy production at the cellular level. It supports heart health and helps combat the tiredness that comes with physical and mental strain.

Especially beneficial for people over 30, as natural levels decline with age.

9. B-Complex Vitamins

B vitamins are key players in converting food into energy. A good B-complex supplement can reduce fatigue and support brain function, helping you stay energised throughout the day.

Look for methylated forms for better bioavailability.

10. Ginkgo Biloba

An ancient herbal remedy known for improving blood flow to the brain, Ginkgo can enhance focus, memory, and mental clarity — especially helpful during long work sessions.

Works best when taken consistently over a few weeks.

Final Thoughts

Supplements aren’t magic pills — but they are powerful tools when combined with daily healthy habits. Focus on building a strong foundation: quality sleep, balanced nutrition, movement, and mindfulness. Then, layer in these supplements to support your natural energy and focus every day.

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