NMN: What the Latest Human Studies Reveal About Anti-Aging

NMN is one of the most talked-about supplements in longevity—but what do real human clinical trials actually show? Below is a clear, science-backed roundup, updated with accurate study sources, so you can easily check the data yourself.

1. NAD+ Levels Increase Safely in Humans

A randomized, dose-ranging clinical trial found that oral NMN (300–900 mg/day) significantly increased blood NAD+ levels after 30 and 60 days, and was well tolerated. Higher doses also improved walking endurance and preserved biological age markers. View the clinical trial details. :contentReference[oaicite:1]{index=1}

2. Improved Physical Function & Energy

In a controlled trial with older subjects (6–12 weeks of 250 mg/day NMN), participants showed measurable increases in grip strength and gait speed—two clinically relevant markers of vitality. Read more about the physical improvements. :contentReference[oaicite:2]{index=2}

3. Strong Safety Profile

Another placebo-controlled study administered 1,250 mg daily NMN for 4 weeks to healthy adults. No serious adverse events were reported, affirming NMN’s tolerability even at higher doses. See the full safety data. :contentReference[oaicite:3]{index=3}

4. Better Insulin Sensitivity in Women

A study involving postmenopausal prediabetic women demonstrated that NMN improved muscle insulin sensitivity—suggesting metabolic benefits in a group at higher risk for diabetes. (Source: aggregated review summarizing human evidence) :contentReference[oaicite:4]{index=4}

5. Human Tolerability Across Doses

A recent overview confirmed that NMN doses ranging from 100–1,250 mg/day are well tolerated across various clinical trials (3–12 weeks), involving adult participants of different health backgrounds. Learn more here. :contentReference[oaicite:5]{index=5}

Summary of Study Insights

• NMN boosts blood NAD+ safely with daily doses between 300–1,250 mg
• Improvement in strength, walking speed, and metabolic markers seen within 6–12 weeks
• Strong safety profile in healthy adults—even at higher doses

Real-World Implication

While the science is promising, combining NMN supplementation with a healthy lifestyle provides the best foundation for long-term benefits.

Why My Dailys Chose Clean NMN

We only use 3rd-party tested NMN, free from fillers or additives. Fit for daily use, aligned with current scientific findings. Explore our NMN product here.

Disclaimer: This information is educational and not medical advice. Consult a healthcare provider before starting any new supplement.